ea0005p74 | Cytokines and Growth Factors | BES2003
Zarkesh-Esfahani H
, Pockley A
, Hellewell P
, Weetman A
, Ross R
Background: Leptin, the satiety hormone that is produced by adipose tissue appears to act as a link between nutritional status and immune function, and it has been shown to elicit a number of immunoregulatory effects, including the promotion of T cell proliferative responses, and the elicitation of pro-inflammatory cytokines from T cells and monocytes. Given that leptin deficiency is associated with an increased susceptibility to infection, and that polymorphonuclear neutrophi...